How are prosthetic groups different from co-f | vedclass

Name: Exam Paper Generator | JEE NEET Paper Generator | Vedclass
Brand: Vedclass
Rating: 5 (35 reviews)

Question

(B) Co-factors are non-protein components that bind to an apoenzyme to make the enzyme catalytically active. They are classified into three types: pro

Vedclass · Accepted Answer

Prosthetic groups are tightly bound to the apoenzyme,whereas other co-factors may be loosely bound.

Vedclass · Answer

(B) Co-factors are non-protein components that bind to an apoenzyme to make the enzyme catalytically active. They are classified into three types: prosthetic groups,co-enzymes,and metal ions.$1$. Prosthetic groups are organic compounds that are tightly or strongly bound to the apoenzyme (e.g.,heme in peroxidase and catalase).$2$. Co-enzymes are organic compounds that associate with the apoenzyme only during the course of catalysis and are usually loosely bound (e.g.,$NAD$ and $NADP$).$3$. Metal ions form coordination bonds with side chains at the active site and also form one or more coordination bonds with the substrate (e.g.,$Zn^{2+}$ in carboxypeptidase).Thus,the primary difference is that prosthetic groups are permanently and strongly attached to the apoenzyme,whereas other co-factors (like co-enzymes) are often loosely associated.

How are prosthetic groups different from co-factors?

Similar Questions

The coenzymes $NAD$ and $NADP$ contain which vitamin derivative?

Which of the following is mismatched?

The structural component of tyrosinase is .........

What are the co-factors called that are loosely bound to enzymes?

Which of the following is related to vitamin $B_2$?

Vedclass Test Series

Exam Paper Generator

Online Exam Module